Chronic Care Management
If you treat patients with chronic conditions such as diabetes, hypertension, Alzheimer’s disease, atrial fibrillation, arthritis, depression, or anxiety, you need a reliable way to monitor patient medications and efficacy.
LifeBrite Labs offers a proprietary, non-invasive, urine-based chronic care management (CCM) panel that tests for an extensive list of medicines commonly prescribed for chronic conditions. We help you reconcile medications for polypharmacy patients, monitor adherence, and evaluate the efficacy of current prescriptions. When the CCM panel suggests a medicine is not having the desired effect, we may recommend a pharmacogenomics panel to help you evaluate alternative medications.
According to the CDC, “Approximately one in five new prescriptions are never filled, and among those filled, approximately 50% are taken incorrectly, particularly with regard to timing, dosage, frequency, and duration.” Medication adherence is low and can have staggering consequences.
In a study produced by the World Health Organization, U.S. Pharmacist found that “Nonadherence can account for up to 50% of treatment failures, around 125,000 deaths, and up to 25% of hospitalizations each year in the United States.”
Pharmacogenomic variations may lead some patients to metabolize certain drugs differently. Physicians have a complicated puzzle to solve for each patient in chronic care management, and Lifebrite can help simplify this process.
LifeBrite Laboratories’ Chronic Care Management Panel Includes:
Alcohol Biomarkers
| Name | Cutoffs |
| Ethyl Glucoronide | 500 ng/ml |
| Ethyl Sulfate | 200 ng/ml |
Alkaloids NOS
| Name | Cutoffs |
| Cotinine | 50 ng/ml |
Amphetamines
| Name | Cutoffs |
| Amphetamine | 200 ng/ml |
| Phentermine | 100 ng/ml |
| Pseudoephedrine | 50 ng/ml |
Analgesics (Non-Opioid)
| Name | Cutoffs |
| Acetaminophen | 500 ng/ml |
| Ibuprofen | 500 ng/ml |
| Salicylic Acid | 400 ng/ml |
| Naproxen | 50 ng/ml |
Anti-Anxiety
| Name | Cutoffs |
| Buspirone | 50 ng/ml |
Antidepressants NOS
| Name | Cutoffs |
| Atomoxetine | 50 ng/ml |
| Bupropion | 50 ng/ml |
| Hydroxybupropion | 50 ng/ml |
| Venlafaxine | 100 ng/ml |
| O-Desmethylvenlafaxine | 100 ng/ml |
| Mirtazapine | 25 ng/ml |
| N-Desmethylmirtazapine | 25 ng/ml |
Antidepressants Serotenergic
| Name | Cutoffs |
| Citalopram | 50 ng/ml |
| N-Desmethylcitalopram | 50 ng/ml |
| Duloxetine | 50 ng/ml |
| Fluoxetine | 25 ng/ml |
| Paroxetine | 25 ng/ml |
| Sertaline | 50 ng/ml |
Antidepressants Tricyclic
| Name | Cutoffs |
| Amitriptyline | 50 ng/ml |
| Nortriptyline | 50 ng/ml |
| Protriptyline | 50 ng/ml |
| Doxepin | 30 ng/ml |
Antiepileptics NOS
| Name | Cutoffs |
| Carbamazepine | 50 ng/ml |
| Carbamazepine-10,11 -Epoxide | 50 ng/ml |
| Levetiracetam | 50 ng/ml |
| Topiramate | 50 ng/ml |
Antipsychotics NOS
| Name | Cutoffs |
| Aripiprazole | 50 ng/ml |
| Dehydroaripiprazole | 50 ng/ml |
| Olanzapine | 25ng/ml |
| N-Desmethylolanzpine | 25 ng/ml |
| Risperidone | 10 ng/ml |
| 9-Hydroxyrisperidone | 10 ng/ml |
| Quetiapine | 50 ng/ml |
| Haloperidol | 25 ng/ml |
| Chloropromazine | 25 ng/ml |
| Clozapine | 25 ng/ml |
| N-Desmethylclozapine | 25 ng/ml |
| Ziprasidone | 25 ng/ml |
| Lurasidone | 25 ng/ml |
Benzodiazepines
| Name | Cutoffs |
| Alprazolam | 30 ng/ml |
| a-Hydroxyalprazolam | 30 ng/ml |
| Clonazepam | 40 ng/ml |
| 7-Aminoclonazepam | 40 ng/ml |
| Diazepam | 50 ng/ml |
| Nordiazepam | 40 ng/ml |
| Oxazepam | 40 ng/ml |
| Temazepam | 50 ng/ml |
| Lorazepam | 50 ng/ml |
Buprenorphine/Metabolite
| Name | Cutoffs |
| Buprenorphine | 10 ng/ml |
| Norbuprenorphine | 30 ng/ml |
Cannabinoids Natural
| Name | Cutoffs |
| THC-COOH | 15 ng/ml |
Cardiovascular Drugs NOS
| Name | Cutoffs |
| Atenolol | 50 ng/ml |
| Clonidine | 50 ng/ml |
| Diltiazem | 50 ng/ml |
| Hydrochlorothiazide | 50 ng/ml |
| Metoprolol | 50 ng/ml |
| Propanolol | 50 ng/ml |
| Verapamil | 50 ng/ml |
| Warfarin | 10 ng/ml |
| Amlodipine | 25 ng/ml |
| Clopidogrel | 5 ng/ml |
| Lisinopril | 50 ng/ml |
| Valsartan | 50 ng/ml |
| Irbesartan | 50 ng/ml |
| Rivaroxaban | 50 ng/ml |
ChEI Drug NOS
| Name | Cutoffs |
| Donepezil | 50 ng/ml |
Diabetes Drugs NOS
| Name | Cutoffs |
| Metformin | 100 ng/ml |
| Sitagliptin | 50 ng/ml |
| Pioglitazone | 10 ng/ml |
| Glipizide | 10 ng/ml |
| Glyburide | 10 ng/ml |
Gabapentin
| Name | Cutoffs |
| Gabapentin | 1000 ng/ml |
Methylphenidate/Metabolite
| Name | Cutoffs |
| Methylphenidate | 50 ng/ml |
| Ritalinic Acid | 50 ng/ml |
NSAIDS Drugs NOS
| Name | Cutoffs |
| Diclofenac | 50 ng/ml |
| 4-Hydroxydiclofenac | 50 ng/ml |
| Indomethacin | 50 ng/ml |
| Celecoxib | 50 ng/ml |
Opiates
| Name | Cutoffs |
| Morphine | 50 ng/ml |
| Hydromorphone | 50 ng/ml |
| Codeine | 50 ng/ml |
| Dihydrocodeine | 50 ng/ml |
| Hydrocodone | 50 ng/ml |
| Norhydrocodone | 50 ng/ml |
Opioids and Opiate Analog
| Name | Cutoffs |
| Naloxone | 10 ng/ml |
Oxycodone/Metabolites
| Name | Cutoffs |
| Oxycodone | 50 ng/ml |
| Noroxycodone | 50 ng/ml |
| Oxymorphone | 50 ng/ml |
Propoxyphene/Metabolite
| Name | Cutoffs |
| Propoxyphene | 100 ng/ml |
| Norpropoxyphene | 100 ng/ml |
Pregabalin
| Name | Cutoffs |
| Pregabalin | 150 ng/ml |
Sedative Hypnotics (Non-Benzo)
| Name | Cutoffs |
| Zaleplon | 10 ng/ml |
| Zolpidem | 10 ng/ml |
| Zolpidem Phenyl-4-Carboxylic Acid | 10 ng/ml |
Skeletal Muscle Relaxants
| Name | Cutoffs |
| Baclofen | 50 ng/ml |
| Carisoprodol | 100 ng/ml |
| Cyclobenzaprine | 50 ng/ml |
| Meprobamate | 200 ng/ml |
Statins Drug(s) NOS
| Name | Cutoffs |
| Atorvastatin | 10 ng/ml |
| Pitavastatin | 10 ng/ml |
| Rosuvastatin | 10 ng/ml |
Tramadol/Metabolite
| Name | Cutoffs |
| Tramadol | 100 ng/ml |
| O-Desmethyltramadol | 100 ng/ml |
Triptans Drug(s) NOS
| Name | Cutoffs |
| Sumatriptan | 50 ng/ml |
| Zolmitriptan | 50 ng/ml |