Inherited cancer screening by doctor.

Inherited Cancer Screening

With next-generation genetic sequencing technology, LifeBrite Labs can now screen your patients for pathogenic genetic variants which may put them at a higher risk of developing certain kinds of cancer. Empowered with this information, you and your patients can then discuss appropriate preventative measures.

LifeBrite offers test panels for breast cancer, prostate cancer, pancreatic cancer, gastric cancer, melanoma, lung cancer, renal cancer, and tumor syndromes, as well as a comprehensive cancer panel.

The medical community has witnessed the firsthand benefits of pre-cancer screenings for patient populations especially with cervical cancer. According to the CDC, cervical cancer was once “the leading cause of cancer death for women in the United States.” Papanicolaou (Pap) tests began to be more widely used in cervical screenings in the 1950s and 1960s, and, as a result, by 2009, cervical cancer incidence and mortality was down by 75%. The benefits of pre-screening are undeniable, and Lifebrite’s genetic sequencing technology is the next step in the evolution of preventative cancer tests in healthcare.

LifeBrite Laboratories’ Inherited Cancer Testing Includes:

LBL ICGx-Female Reproductive Tract Cancers Panel

Gene GHR OMIM
BRCA1
BRCA2
BRIP1
EPCAM
MLH1
MSH2
MSH6
PMS2
RAD51C
RAD51D
STK11

LBL ICGx-Breast Cancer Panel

Gene GHR OMIM
ATM
BARD1
BRCA1
BRCA2
BRIP1
CDH1
CHEK2
MRE11A
MUTYH
NBN
NF1
PALB2
PTEN
RAD50
RAD51C
STK11
TP53

LBL ICGx-Prostate Cancer Panel

Gene GHR OMIM
BRCA1
BRCA2
CHEK2
ELAC2
NBN
TP53

LBL ICGx-Pancreatic Cancer Panel

Gene GHR OMIM
APC
BRCA1
BRCA2
CDKN2A
EPCAM
MEN1
MLH1
MSH2
MSH6
PALLD
PMS2
STK11
TP53

LBL ICGx-Gastric Cancer Panel

Gene GHR OMIM
APC
BMPR1A
CDH1
EPCAM
MLH1
MSH2
MSH6
PMS2
SMAD4
STK11

LBL ICGx-Melanoma Panel

Gene GHR OMIM
CDK4
CDKN2A

LBL ICGx-Lung Cancer Panel

Gene GHR OMIM
STK11
TP53

LBL ICGx-Renal Cancer Panel

Gene GHR OMIM
APC
EPCAM
MET
MLH1
MSH2
MSH6
MUTYH
PMS2
PTEN
TP53
VHL

LBL ICGx-Tumor Syndromes Panel

Gene GHR OMIM
FANCC
HRAS
PTCH1
RET

LBL ICGx-Comprehensive Hereditary Cancer Panel

Gene GHR OMIM
APC
ATM
BARD1
BMPR1A
BRCA1
BRCA2
BRIP1
CDH1
CDK4
CDKN2A
CHEK2
ELAC2
EPCAM
FANCC
HRAS
MEN1
MET
MLH1
MRE11A
MSH2
MSH6
MUTYH
NBN
NF1
PALB2
PALLD
PMS2
PTCH1
PTEN
RAD50
RAD51
RAD51C
RAD51D
RET
SMAD4
STK11
TP53
VHL